Whole Genome Sequencing of the World’s Oldest People
Supercentenarians (110 years or older) are the world’s oldest people. Seventy four are alive worldwide, with twenty two in the United States. We performed whole-genome sequencing on 17 supercentenarians to explore the genetic basis underlying extreme human longevity. The DNA sequence of all 17 supercentenarian genomes is available as a resource to assist the discovery of the genetic basis of extreme longevity in future studies. This study was a collaboration between Stanford University (Dr. Stuart K. Kim), the Institute of Systems Biology (Dr. Leroy Hood), and the Supercentenarian Research Foundation (Dr. L. Stephen Coles).
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